Sildalist 120 mg (Sildenafil/Tadalafil)

What is Sildalist 120 mg?

Sildalist 120 mg is marketed as a combination ED tablet that claims to contain sildenafil 100 mg and tadalafil 20 mg. In the US, the FDA has not approved it as an ED treatment. Some sellers list it as Sildalist 100/20 mg. The 120 mg figure refers to the combined stated amounts of the two active ingredients. It is neither 120 mg of tadalafil nor 120 mg of sildenafil.

Two drugs from the same class in one tablet make the formulation different from a plain high-dose ED pill. Standard prescribing information for sildenafil and tadalafil does not support combining PDE5 inhibitors.

What Are the Uses of Sildalist 120 mg?

Sildalist 120 mg is used to treat an ED condition in which a person has difficulty achieving or maintaining an erection firm enough for sexual activity.

Sildenafil and tadalafil are both PDE5 inhibitors that act on the nitric oxide–cGMP pathway. They block PDE5, so cyclic GMP stays higher in penile tissue. That lets smooth muscle relax and blood flow rise when stimulation happens.

Each ingredient has its own approved uses and dosing that do not match this combo. Tadalafil is also prescribed for BPH. Sildenafil is also available in other forms for other indications. Do not assume those uses carry over to a Sildalist tablet.

How Does Sildalist 120 mg Work?

Both sildenafil and tadalafil inhibit PDE5, and that makes sure the cGMP level is maintained while having sexual activity. This eventually relaxes the smooth muscle in the wall and causes an increased blood flow to the penis. Because both medicines act through the same pathway, combining them may increase adverse effects, including excessive reductions in blood pressure.

For up to 36 hours following a treatment, Sildalist dosages can improve erectile function.

How to Take a Sildalist 120 mg Tablet?

Do not self-medicate with a sildenafil–tadalafil combination. The safety and efficacy of combining PDE5 inhibitors have not been established, and the approved prescribing information advises against their use.

A few basics:

1. Swallow with water. No crushing or chewing.
2. Never take more than prescribed.
3. Skip other PDE5 inhibitors.
4. Don’t take it more often than your physician recommends.
5. Tell your doctor about every prescription, OTC product, and supplement you take.

Sildenafil is usually taken before sex. A high-fat meal can slow sildenafil absorption. 

How Long Does Sildalist 120 mg Last?

You cannot reduce the duration to “120 mg lasts X hours” because two different drugs are involved.

Since Sildalist combines both activities, the overlap may also stretch out side effects or make them hit harder in some men.

Sildalist 120 mg Dosage

The following doses refer to FDA-approved tadalafil used as a single medication and should not be interpreted as dosing instructions for Sildalist.

The recommended tadalafil dosage is 10 mg, depending on tolerability and response. However, the doctor can increase or decrease it as per the need. ED treatment is usually started at 5mg. 

Available Strengths and Related Options

Sildalist comes in a single strength at PrimeRx Medicine, combining 100 mg sildenafil with 20 mg tadalafil. If it isn’t right for you, your doctor can suggest a related option with similar ingredients, so check with them before you switch.

• Cenforce 100 mg
• Fildena 100 mg
• Cenforce 200 mg
• Fildena 150 mg
• Cenforce 150 mg
• Vidalista 20 mg
• Kamagra Oral Jelly

Sildalist 120 mg Side Effects

Two PDE5 inhibitors mean side effects from either one can show up. Possible effects:

1. Headache
2. Facial flushing
3. Indigestion
4. Back or muscle discomfort
5. Nasal congestion
6. Dizziness
7. Nausea
8. Vision changes
9. Palpitations or a faster heartbeat
10. A temporary drop in blood pressure

Dizziness, fainting, excessive blood pressure reduction, and other cardiovascular effects may be more likely when sildenafil and tadalafil are taken together, since both widen blood vessels. Get urgent help if an erection lasts 4 hours or longer, or if you notice sudden vision loss, sudden hearing loss, severe chest pain, or fainting.

Sildalist 120 mg Medicinal Interactions

Sildenafil and tadalafil can interact with several medicines and substances, including:

1. Nitrates: Sildenafil and tadalafil can significantly increase the blood pressure-lowering effect of nitrates. Using them together is contraindicated.
2. Alpha blockers: These can add to the blood pressure drop. PDE5 inhibitors used with alpha-blockers may cause an additional reduction in blood pressure. Sildenafil prescribing information recommends that patients be stable on alpha-blocker therapy before sildenafil is initiated at the lowest recommended dose.
3. Blood pressure medicines: Additive reduction is possible.
4. Other drugs that are PDE5 inhibitors: Sildenafil, tadalafil, vardenafil, avanafil, and any other medications to treat erectile dysfunction could only be added in consultation with a doctor.    
5. Strong CYP3A4 inhibitors: These may lead to an increasing rise in the level of sildenafil or tadalafil used, leading to a higher probability of side effects.
6. Alcohol: When drunk excessively, alcohol increases side effects like dizziness and blood pressure changes.

Please provide your doctor with a complete list of all medicines and supplements before starting.

Safety Advice

Blood Pressure Conditions

Sex puts extra demand on the heart. Men with significant heart disease, unstable angina, uncontrolled blood pressure, or a recent serious cardiac event should talk to a doctor before using PDE5 inhibitors. People with cardiovascular risk factors should seek medical advice before using ED medicines.

Liver Problems

Sildenafil and tadalafil are processed in the liver. Liver impairment can change drug processing and raise exposure. Tell your doctor about hepatitis, cirrhosis, abnormal liver tests, or any other liver condition. A different dose or treatment may fit better.

Kidney Problems

Kidney impairment can affect how some medicines are handled. Your doctor should know about reduced kidney function before prescribing an ED medicine. If the effects seem weak, please do not increase the dosage on your own.

Avoid Combining ED Medicines

The safety and efficacy of combining tadalafil with other PDE5 inhibitors are not established, and patients are advised against it.

FAQS

Is Sildalist 120 mg habit-forming or addictive?

Sildenafil and tadalafil are typically considered non- addictive. Nonetheless, a few individuals may come to depend psychologically on ED treatment in relation to their sexual performance or self-assurance.

Does Sildalist 120 mg affect male fertility or sperm count?

Available evidence has not established that therapeutic use of PDE5 inhibitors causes male infertility. However, evidence specifically concerning an unapproved sildenafil–tadalafil combination such as Sildalist is limited.

Can I drink grapefruit juice while taking Sildalist 120 mg?

Drinking grapefruit juice is not recommended. Grapefruit juice is identified as a CYP3A4 inhibitor; therefore, it can have an effect on your body’s capacity to metabolize sildenafil or tadalafil. As a result, you could find yourself with heightened blood concentrations of the drug, which increases the likelihood of experiencing adverse effects.

How should I store Sildalist 120 mg?

Store at room temperature, away from excessive heat, light, and moisture. Keep out of reach of children and animals. Do not use it after the expiry date, which is shown on the pack.

Does Sildalist 120 mg cure erectile dysfunction permanently?

No. ED medicines such as sildenafil and tadalafil treat symptoms of erectile dysfunction but do not permanently cure the underlying cause.